Drug interactions between HIV / AIDS drugs and anti-TB drugs are particularly problematic.. About Johnson & Johnson Pharmaceutical Research & Development, LLCJohnson & Johnson Pharmaceutical Research & Development, is part of Johnson & Johnson, the world broadly based manufacturer of health care products. Johnson & Johnson Pharmaceutical Research & Development, based in Raritan, New Jersey , has offices throughout Europe and the United States. Johnson & Johnson Pharmaceutical Research & Development uses, drug discovery, evaluation and drug development in a variety of therapeutic areas to address unmet medical needs worldwide. The company focuses on major therapeutic areas hematology, oncology, infectious disease, obesity and metabolic disorders, neurology and psychiatry, pain and women’s health.
The compound was their sister company, Tibotec Pharmaceuticals Limited, evaluation lead compounds are transferred to HIV / AIDS for clinical development.
In mouse models the studies showed that a cocktail reduces regimen with this compound bacterial load after a month on the same level as the currently used regimen after two months of treatment, normal shortening treatment treatment by 50 % after two months treatment with the R207910 containing cocktail could no TB bacilli are more isolated from the lung, a finding that the French group, these studies as ‘unprecedented. ‘.. About R207910A French chemist from the Johnson & Johnson pharmaceutical group synthesized the substance and the team in Beerse, Belgium discovered its anti-TB action.Prof Rothwell and colleagues performed a systematic review all the relevant observational to see if they came to the same conclusions and when so, what could to be said about dose and regularity of the aspirin, in and use of other non-steroidal anti-inflammatory drug may affect and as characteristics of the patient of situation.
Also were former studies the nature be observed, 2,500 tuberculosis patients use of aspirin through colon cancer patients and healthy subjects and randomization participant from the beginning. Various doses and of a placebo , and it after their advancement.
‘Use of 300 mg or more aspirin a day for approx. 5 years active in primary prevention by cancer is in randomized controlled trials, with a latency of approximately 10 years, in consistent with evidence from observational studies. ‘.