As the pollution is normally chronic, this can lead to chronic swelling in the affected organs, such as the heart. Air flow monitoring in metropolitan Mexico Town has shown that pollution characteristics differ between north Mexico City and south Mexico Town. Residents in the south aspect face higher degrees of endotoxins than citizens of north Mexico Town. The research team’s previous research found that mice exposed to surroundings from south Mexico Town had higher levels of inflammation in the heart muscle mass than mice subjected to north Mexico City air flow. They hypothesized that the difference could be linked to the difference in endotoxin levels.Ad libitum usage of low-fat diets results in short-term weight reduction,1 and low-carbohydrate, high-protein, and high-fat diets may result in substantial weight loss as compared with that achieved with other types of diets.2 However, the weight loss is normally not sustained beyond 1 year. 3 Greater weight reduction with low-carbohydrate diets may be ascribed to the satiating effects of high protein content,4 and there is increasing curiosity in the efficacy of diet programs which have a high protein quite happy with a moderate carbohydrate and extra fat content.5-7 A diet with a minimal glycemic index might have beneficial effects on body weight and body composition8,9 and on particular risk factors in overweight persons,9,10 however the effectiveness of advertisement libitum consumption of low-glycemic-index diets for excess weight control is controversial.9 THE DIETARY PLAN, Obesity, and Genes study is a pan-European, multicenter, randomized, dietary-intervention study designed to assess the efficacy of moderate-fat diets that differ in protein content and glycemic index for preventing weight regain and obesity-related risk factors after weight loss.