This failing of Dimebon, that was hypothesized to act as a mitochondrial pore blocker, along with the repeated failures of each drug studied for removing beta amyloid from the brain in an effort to manage Alzheimer’s disease, suggests that novel mechanisms of action that try to modify the condition itself, than treat symptoms rather, are necessary, said Cameron Durrant, MD, MBA, Executive Chairman of the ANAVEX Panel of Directors. ANAVEX is certainly getting ready to enter Phase 1 clinical trials with ANAVEX 2-73, its lead compound for the treating Alzheimer’s disease, this year later. ANAVEX 2-73 is a first of a new course of oral, disease-modifying medicines for the treatment of Alzheimer’s disease, which utilize a strategy that targets neither amyloid, nor tau, nor mitochondrial pore blockade.On the other side, feminine infertility issues because of problems associated with fallopian tubes often, ovulation and other physical problems with the uterus. In addition, blocked fallopian tubes, Uterine and PCOS fibroids are some typically common factors behind female fertility. Like males diet, age group, stress, alcohol, smoking, hormonal change are factors that increase infertility in females. As we grow older, our reproductive system’s ability reduces. Ovaries become less in a position to release eggs, amount of sperm reduce, chance of miscarriage increases, sperm and eggs are not healthy enough to achieve a successful pregnancy.